The purpose of this paper is the application of an internal visualization method for contaminant distribution analysis and quantification in filter cartridges, based on X-Ray Computerized Tomography (XCT). The cartridge filters were contaminated with glass beads and scanned in a medical device. The scanning process was carried out both with and without contaminant in the filter to compare the attenuation coefficient of the clean filter and the contaminated filter. Hundreds of images were collected and the mapping of the particles in each section of the filter were analyzed using the segmentation technique, based on the difference between contaminant (glass beads) and filter (wound polypropylene fibers) attenuation coefficients. The move relevant images were selected and quantitatively analyzed. The shape of the distribution is also presented. Finally, the results show the potential of the technique for the proposed analysis.