Influences of cosolvents on the solubilities of fatty acids (palmitic acid (C15H31COOH) and stearic acid (C17H35COOH)) and higher alcohols (cetyl alcohol (C16H33OH) and stearyl alcohol (C18H37OH)) in supercritical carbon dioxide were measured by using a flow-type apparatus. Experiments were carried out at 308.2 K under 9.9, 14.8 and 19.7 MPa. Ethanol and octane were used as cosolvents. The concentration of cosolvent was up to 10 mol%. The experimental results were correlated by the regular solution model coupled with the Flory-Huggins theory using the local composition of cosolvent around the solute molecule.