Journal of Molecular Catalysis A-Chemical, Vol.285, No.1-2, 150-154, 2008
Molecular shape selectivity of hydrotalcite in mixed aldol condensations of aldehydes and ketones
The work has engaged in the effect of activated hydrotalcite for aldol condensation of cyclic and linear ketones with n-heptanal and norborn-5-ene-2-carbaldehyde. A significant configuration selectivity of the catalyst was found, when the condensation of the cyclic ketones was strongly prefered in comparison with condensation of the linear ones. The mechanism of the surface reaction was predicted by the methods of molecular modeling. (c) 2008 Elsevier B.V. All rights reserved.