Chemical Industry and Technology, Vol.2, No.2, 152-155, June, 1984
[기술] Scale-Up Studies of a Fluorination of a Steroid with Perchloryl Fluoride
A practical and safe method has been developed for the reaction of perchlory fluoride with 1,2-dihydrobetamethasone-3-enol-17,21-triacetate. This fluorination generates significant amounts of several by-products, and the development of condictions to minimize these by-products is described.