On the Ni(1 1 0) surface, H+ and O+ are normally detected by electron-stimulated desorption (ESD). However, C+, N+, S+ are normally insensitive to ESD measurement. In this report S+ signal has benn significantly detected by the ESD from the Ni(1 1 0) surface. Behavior of S+ has been observed in the variation of time-of-flight (TOF)-ESD spectra during heating.