Au/Ti-MWW catalysts were prepared by the impregnation of HAuCl4 on Ti-MWW. Its structure and properties were characterized by X-ray diffraction, N-2 adsorption and UV-visible. The oxidation reactions of thiophene (TH), benzothiophene (BT), dibenzothiophene (DBT) and 4,6-dimethyl-dibenzothiophene (DMDBT) were investigated at mild reaction conditions using H2O2 as oxidant. The results showed that An loading could significantly promote the activity of Ti-MWW for oxidative desulfurization.