Catalysis Letters, Vol.125, No.3-4, 315-319, 2008
Synthesis of alpha-amino phosphonates by three component condensation of carbonyl compound, amine, and dialkyl phosphite using Yttria-zirconia based Lewis acid catalyst
An efficient Yttria-zirconia Lewis acid catalyzed one-pot synthesis of alpha-amino phosphonates by three component coupling reaction of a carbonyl compound amine and dialkyl phosphates is described in good to high yield.
Keywords:alpha-amino phosphonates;Yttria-zirconia based Lewis acid catalyst;three component coupling