Mesoporous TiO2 whisker was loaded with gold (denoted as Au/T(t), t represents the calcination temperature of support) by deposition-precipitation with urea (DPU) and then used in low-temperature CO oxidation. Disparate morphologies were obtained for the gold deposited on different TiO2 whisker samples while the particle sizes were in a similar range. The better performance of Au/T(600) than Au/T(300) was attributed to the increased contacting area of gold/titania and the strong interaction between gold and well-crystallized suppot surface.