An analysis is presented to investigate the effect of thermophoresis particle deposition and variable viscosity on non-Darcy MHD mixed convective heat and mass transfer of a viscous, incompressible and electrically conducting fluid past a porous wedge in the presence of chemical reaction. The wall of the wedge is embedded in a uniform non-Darcian porous medium in order to allow for possible fluid wall suction or injection. The governing partial differential equations of the problem, subjected to their boundary conditions, are solved numerically by applying an efficient solution scheme for local nonsimilarity boundary layer analysis. Numerical calculations are carried out for different values of dimensionless parameter in the problem and an analysis of the results obtained show that the flow field is influenced appreciably by the applied magnetic field. The results are compared with those known from the literature and excellent agreement between the results is obtained. (C) 2009 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.