The effective direct electrocatalytic oxidation of glucose in alkaline solution at electrochemically deposited Pt nanoparticle-modified glassy carbon electrode is reported, for the first time. Catalytic oxidation of glucose was observed and comparison to a previously reported system based oil gold nanoparticles showed a significant positive catalytic effect of the prepared electrodes in the current study: a considerable shift of the oxidation peak potential by ca. 280 mV was found. 1-t measurements revealed that only a very minute Pt loading as small as ca. 9.2 x 10(-3) mg cm(-2) is required to obtain comparable Current densities with those at All nanoparticles.