The objective of this work was to investigate nucleate pool boiling heat transfer performance and mechanism of R134a and R142b on a twisted tube with machine processed porous surface (T-MPPS tube) as well as to determine its potential application to flooded refrigerant evaporators. In the experimental range, the boiling heat transfer coefficients of R134a on a T-MPPS tube were 1.8-2.0 times larger than those of R134a on a plain tube. In addition, the developed experimental correlations verified that the predictions of the heat transfer coefficients of boiling R134a and R142b on a T-MPPS tube at the experimental conditions were considerably accurate.