Disturbances that spread plant-wide in a chemical process pose challenges to maintenance staff. Connections within the plant and the presence of multiple causal paths mean it is not straightforward to locate the root disturbance because the effects can propagate and be detected elsewhere. Measurement-based methods use quantitative process history to generate hypotheses about the root cause, while a separate strand of work in the literature has used causal maps and digraphs. It has been reported that both approaches can give spurious solutions, however. The idea behind this article is to reduce the number of spurious solutions by combining basic and readily available information about the connectivity of the process with the results from causal measurement-based analysis. Connectivity information is captured from an XML description of the process schematic that complies with the CAEX schema. The capabilities of the approach and its potential for future development are discussed. (C) 2008 Elsevier Ltd. All rights reserved.