This paper discusses the experimental results of the water-gas shift reaction over supported nickel catalysts in comparison to thermodynamic equilibrium composition at the same reaction conditions. The effects of different supports on the performance of H-2 production over nickel-supported catalysts are also evaluated at both low and high temperatures. Ceria-promoted nickel catalyst supported on powder alumina (Ni/CeO2-Al2O3) demonstrated excellent performance. The catalyst was not stable at low temperature (250 degrees C) but showed good stability at high temperature (450 degrees C). At 450 degrees C, with a catalyst loading of 0.05 g, CO/S (S = steam) ratio of 1:3, and gas hourly space velocity (GHSV) approximate to 200 L h(-1) g(cat)(-1), the activity of Ni/CeO2-Al2O3 was 95% with a H-2 yield of 52% and a H-2 selectivity of 73%.