A great majority of modern buildings are equipped with Energy Management and Control Systems (EMCS) which monitor and collect operating data from different components of heating ventilating and air conditioning (HVAC) systems. Models derived and tuned by using the collected data can be incorporated into the EMCS for online prediction of the system performance. To that end, HVAC component models with self-tuning parameters were developed and validated in this paper. The model parameters were tuned online by using a genetic algorithm which minimizes the error between measured and estimated performance data. The developed models included: a zone temperature model, return air enthalpy/humidity and CO2 concentration models, a cooling and heating coil model, and a fan model. The study also includes tools for estimating the thermal and ventilation loads. The models were validated against real data gathered from an existing HVAC system. The validation results show that the component models augmented with an online parameter tuner, significantly improved the accuracy of predicted outputs. The use of such models offers several advantages such as designing better real-time control, optimization of overall system performance, and online fault detection. (C) 2008 Elsevier B.V. All rights reserved.