Polymethacrylamide (PMAA) was coated onto the surfaces of Kevlar fabrics through the in situ polymerization of methacrylamide (MAA) within coating polymer binders. Upon chlorine bleach treatment, the amide groups of the coated PMAA side chains were transformed into stable acyclic N-halamines. The resultant fabric materials provided potent, durable, and rechargeable biocidal activities against E. coli (gram-negative bacteria), S. aureus (gram-positive bacteria), C tropicalis (fungi), MS2 virus, and Bacillus subtilis spores. The excellent thermal and mechanical properties of the original Kevlar fabrics were successfully retained after the coating treatment.