In this work, ethylene glycol (EG) (1) + water (2) solutions (EGWs) were used as the promising medium for the absorption and desorption processes of SO2. Desorption data showed that SO2 can be desorbed easily from EGWs + SO2 at 333 K. Phi(1) = 70-90% (volume fraction of EG in EGWs) were considered as reasonable compositions of desulfurization solution. Considering the industrial flue gas desulfurization (FGD) processes, Phi(1) = 80% EGW (approximately 0.5 molar fraction of EG) was confirmed as the optimum composition of desulfurization solution. When conventional UV, FTIR, and H-1 NMR spectroscopic techniques were used for inspection of spectral changes of SO2 in EGWs, the spectral results suggest that SO2 can interact with EG by hydrogen bonds.