In this paper, a systematic procedure to design multivariable controllers that have options for selective decoupling of different structures (e.g., full or partial decoupler) is proposed. The controller structure is determined based on in analysis of relative load gain (RLG). For controller design, the adjoint of a template matrix is provided to design the MIMO decoupler that is needed for a given process. In the case where decoupling is desirable, according to the number of zero deficiency that the adjoint of the template matrix has, a pole-zero compensator is incorporated to preserve the properness of the decoupling controller and to define the decoupled open-loop dynamics. By incorporating the decoupler, the controller in the main loop is synthesized for disturbance rejection. Stability robustness of the system is tuned using measures of modeling errors in the decoupled open-loop process. Simulation examples are used to illustrate the proposed method and show its effectiveness in disturbance rejection in MIMO systems.