Convection heat transfer of CO2 at super-critical pressures during cooling in a vertical small tube with inner diameter of 2.00 mm was investigated experimentally and numerically. The local heat transfer coefficients were determined through a combination of experimental measurements and numerical Simulations. This study investigated the effects of pressure, cooling water mass flow rate, CO2 mass flow rate, CO2 inlet temperature, flow direction, properties variation and buoyancy on convection heat transfer in small tube. The results show that the local heat transfer coefficients vary significantly along the tube when the CO2 bulk temperatures are in the near-critical region. The increase of specific heat and turbulence kinetic energy due to the density variation leads to the increase of the local heat transfer coefficients for upward flow. The buoyancy effect induced by density variation leads to a different variation trend of the local heat transfer coefficients along the tube for upward and downward flows. The numerical simulations were conducted using several kappa-epsilon turbulence models including the RNG kappa-epsilon model with a two-layer near wall treatment and three low-Reynolds number eddy viscosity turbulence models. The simulations using the low-Reynolds number kappa-epsilon model due to Yang-Shih has been found to be able to reproduce the general features exhibited in the experiments, although with a relatively large overestimation of measured wall temperatures. A better understanding of the mechanism of properties variation and buoyancy effects on convection heat transfer of CO2 at super-critical pressures in a vertical small tube during cooling has been developed based on the information generated by the simulation on the detailed flow and turbulence fields. (C) 2009 Elsevier Ltd. All rights reserved.