The potential of photo-catalysis as a self cleaning process is investigated for application inside refrigerator cabinets, taking advantage of the well known oxidative properties of titanium dioxide (anatase form). A low temperature in situ synthesis was adopted to obtain a catalytic layer over a polystyrene (PS) support. The synthesised material was characterised by SEM, XRD and BET analyses. Photo-catalytic activity towards organic dirt decomposition was measured through the oxidation of various organic dyes, as the perceivable decolouring of the dirt represents a clear activity indicator for users. The selected contaminants (Methylene Blue and Ortho-Cresole Red) and two refrigerator wastes (orange juice and tomato pulp) were tested at different concentrations. The results were evaluated through by colorimetric analysis. A clear photo-catalytic effect of dye discolouring was detected on the coated samples. The discolouring effect of the coated samples was comparable with that observed on the anatase powder.