Journal of Applied Microbiology, Vol.107, No.4, 1258-1268, 2009
Effects of thymol and diphenyliodonium chloride against Campylobacter spp. during pure and mixed culture in vitro
Aims: To determine if the purported deaminase inhibitors diphenyliodonium chloride (DIC) and thymol reduce the growth and survivability of Campylobacter. Methods and Results: Growth rates of Campylobacter jejuni and Camp. coli were reduced compared to unsupplemented controls during culture in Muellar-Hinton broth supplemented with 0 center dot 25 mu mol DIC or thymol ml 5 log(10) CFU from controls after 24 h pure culture in Bolton broth supplemented with 0 center dot 25 or 1 center dot 0 mu mol DIC ml 3 log(10) CFU from controls after 24 h mixed culture with porcine faecal microbes in Bolton broth supplemented with 0 center dot 25 or 1 center dot 0 mu mol DIC ml