Enantioselective membrane was prepared using ethyl cellulose (EC) as membrane material. The flux and permselective properties of membrane using aqueous solution of (R,S)-2-phenyl-1-propanol as feed solution was Studied. The employed membrane process was a pressure driven process. All kinds of important conditions including preparation and operation of membranes were investigated in this experimentation. When the membrane was prepared with 18 wt % EC, 20 wt %. N,N-dimethylformamide in casting solution, 13 min evaporation time and 0 degrees C temperature of water bath for the gelation of the membrane, and the operating pressure and feed solution of (R,S)-2-phenyl-1-propanol were 0.2 MPa and 1.5 mg/mL, respectively, over 90% of enantiomeric excess (e.e.) and 44.2 (mg/m(2) h) of flux were obtained. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 112: 2516-2521,2009