Nanostructured metal matrix composites (NMMCs) in large-dimension billets were fabricated by hot isostatic pressing (HIPing) of cryomilled powders consisting of AA2024 alloy reinforced by 25 wt.% SiC particles. Microstructure of the bulk nanostructured composites and cryomilled powders was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). In addition, mechanical properties of the bulk nanocomposites were also addressed.