화학공학소재연구정보센터
Journal of the American Chemical Society, Vol.130, No.21, 6662-6662, 2008
Synthesis of multimeric MR contrast agents for cellular imaging
We have prepared a series of molecular multimeric MR contrast agents for cell labeling that are easy to synthesize, relatively low molecular weight, and biocompatible. The relaxivities of the agents range from 17 to 85 mM(-1)s(-1). Cellular uptake is concentration dependent and viability is excellent. MR images of cell pellets reveal a marked increase in observed signal intensity.