Journal of the American Chemical Society, Vol.130, No.28, 8892-8892, 2008
Nanometer arrays of functional light harvesting antenna complexes by nanoimprint lithography and host-guest interactions
We show an approach based on combination of site-directed mutagenesis, NIL and multivalent host-guest interactions for the realization of engineered ordered functional arrays of purified components of the photosynthetic system, the membrane-bound LH2 complex. In addition to micrometer-scale patterned structures, we demonstrated the use of nanometer-scale hard NIL stamps to generate functional protein arrays approaching molecular dimensions.