Contamination of active pharmaceutical ingredients and healthcare products with oxidized forms of palladium and platinum are important problems. We report a convenient fluorogenic probe based on the catalyzed aromatic Claisen rearrangement capable of detecting Pd-II and Pt-IV. Using this probe, we can fluorescentty detect Pd-III in functionalized organic compounds and Pt-IV in Pt-0-water without sample pretreatment. This method may find broad applications in the pharmaceutical industry, the environment, and Pd/Pt quality control.