The biomimetic synthesis and structural reassignment of tridachiahydropyrone, tridachiahydropyrone B and tridachiahydropyrone C, isolated from mollusks of the order Sacoglossa, using a sequence of photochemical transformations from a common polyene precursor are described. These complex natural products may act as sunscreens for the producing organism, thus offering protection from harmful UV radiation and oxidative damage.