Alkylation of toluene with methanol has been studied in a fixed bed reactor with a continuous flow system. As a promoter, heteropoly acids and their metal salts were impregnated on Y-zeolite. Catalyst impregnated with lower amount of heteropoly acid showed higher initial activity, and the catalytic activity was enhanced by more electronegative metal ion of heteropoly acid salt impregnated on Y-zeolite. Catalyst calcined at lower temperature showed higher initial activity, but its deactivation rate was faster than that calcined at higher temperature. Catalyst impregnated with BiPMo₁₂O₄₀ showed a good activity and a good regeneration ability of catalytic activity.