Two well-defined triphenylamine-based fluorescent conjugated glycopolymers were easily synthesized through Suzuki coupling polymerization of peracetylated galactopyranosyl-carrying monomer and consequent efficient deacetylation under Zemplen condition. Their structures were characterized using H-1 NMR, IR, and UV-vis spectroscopies. The preliminary insight into carbohydrate-lectin interactions was revealed by the titration of peanut agglutinin (PNA) to one of the final polymers, D-galactose-bearing poly(fluorene-alt-triphenylamine) copolymer (P-2), resulting in a significant fluorescence quenching of the polymer with a Stern-Volmer quenching constant of 1.56 x 10(5) M-1. Whereas no distinct change in the fluorescent properties of P-2 was observed when concanavalin A (Con A) was employed. (C) 2009 Elsevier Ltd. All rights reserved.