The fluidization behavior of the three kinds of nano-particles (TiO2, SiO2, Al2O3) was analyzed in a rotating fluidized bed (RFB). Bed pressure drop, minimum fluidization velocity, bed expansion, entrainment and particle mixing characteristics under various centrifugal accelerations were experimentally investigated. The effects of centrifugal acceleration on agglomerate size and density were analyzed based on a Richardson-Zaki approach coupled with a fractal model. The bed pressure drop behavior showed almost similar to that of A or B-particles of Geldart's classification. Dimensionless particle bed height became smaller when the centrifugal acceleration was larger. Size of agglomerate decreased and its density increased with an increase in centrifugal acceleration. The agglomerate size in the RFB showed smaller than that in other types of fluidized bed system such as vibration and magnetic field as well as in a conventional fluidized bed, and the agglomerate density became larger. Particle entrainment became smaller in the case of the higher centrifugal acceleration. These results confirmed that the RFB can reduce the size of a nano-particle agglomerate and fluidize nano-particles at high gas velocity without any significant entrainment. The RFB is thus expected as more effective gas-solid fluidization system for handling of a large amount of nano-particles than other types of fluidized bed. (C) 2008 Elsevier B.V. All rights reserved.