This article describes a new set of scale-up parameters of spouted beds derived from solid stress analyses. Compared with the first set of scale-up parameters of spouted beds proposed by He et al. [He Y. L, Lim C. J., Grace J. R., Scale-up studies of spouted beds, Chemical Engineering Science, 52 (2), 329-339, 1997], this set introduced a new parameter, the coefficient of restitution of particles, that accounts for the effects of particle-particle collisions in the spout region of a spouted bed. To verify the present set of scale-up parameters, a series of experiments were designed and conducted in two spouted beds of 80 mm and 120 mm in diameter, respectively. operated in the different testing cases consisting of different combinations of the involved scale-up parameters. The results showed that the more closely the scale-up parameters of the spouted beds tested were matched. the higher hydrodynamic similarity could be achieved. The comparisons of the hydrodynamic properties such as fountain height, spout diameter and bed voidage measured in the different testing cases revealed that the coefficient of restitution of particles could significantly impact the particle-particle interactions and thus its effects should be taken into account in scaling-up spouted beds. (c) 2009 Elsevier B.V. All rights reserved.