In this work, the macroporous anion exchange resin - Amberlite FPA51, is proposed as the effective adsorbent for the removal of Acid Blue 74 from aqueous solutions. The sorption mechanism was investigated under static conditions taking into account the phase contact time, solution pH, initial dye concentration, and temperature. The equilibrium data were fitted to the Langmuir, Freundlich, and Dubinin-Radushkevich isotherm models. The maximum monolayer capacity Q0 was 123.8mg/g. The adsorption kinetics was found to follow the pseudo-second order model. The sorption energy was equal to 14.5kJ/mol and indicated that the adsorption process of the dye may be described via a chemical anion-exchange mechanism.