Calorimetry is evaluated for study of the toxic effect of environmental androgens on Schizosaccharomyces pombe cells. The results indicate that androstendione, androstandiendione and dehydrotestosterone inhibited S. pombe heat production rate. Although, the turbidimetric method showed that testosterone (TS) had no influence on growth of S. pombe, calorimetry revealed that there was a shift in growth period in samples with TS. (c) 2008 Elsevier B.V. All rights reserved.