The epoxide rearrangement of beta-pinene oxide into myrtanal was studied in the presence of solid Lewis-acid catalysts. Different metals such as Zr, Sn,Ti, Nb,Ta, Al, and Ga have been incorporated within network positions of zeolite Beta by isomorphous substitution. The materials have been characterized by powdered X-ray diffraction (XRD). IR spectroscopy and by in situ IR spectroscopy on adsorbed molecules (cyclohexanone and pyridine). Among the studied catalysts Zr-Beta gave the best selectivity (up to 94%) in acetonitrile as solvent at practically complete conversion. In this epoxide rearrangement the solvent has to be selected to balance the competitive adsorption of the product. Product desorption is enhanced with acetonitrile which results in a selectivity increase with only a small penalty on the rate of reaction. Zr-Beta has been reused in the batch mode and in a fixed-bed reactor for several times and analysis of the reused catalyst indicated that Zr-Beta is a robust catalyst for the epoxide rearrangement. Leaching of the metal or crystal degradation has not been detected. (C) 2010 Elsevier B.V. All rights reserved.