Kinetics of CO2 desorption from CO2-loaded methyldiethanolamine (MDEA) aqueous solutions were measured in the following conditions : 312-383 K, 25-50 wt% MDEA aqueous solutions CO2 loadings from 5 to 85%. A thermoregulated constant interfacial area reaction cell was operated by measuring the pressure over the solution. Producing a very slight depression in the cell, the time-dependent equilibrium pressure recovery is accurately recorded during batch desorption. Kinetics are in agreement with a fast reaction regime of desorption according to the film theory, For CO2 loadings below 0.50 mol of gas/mol of amine, desorption rates are well predicted by using the kinetic constant and orders determined from absorption experiments for the reaction between CO2 and MDEA. Some discrepancies were pointed out for loadings above 0.50 mol of gas/mol of amine.