In this study, we have measured the solubility of hydrogen in n-hexane and ethanol confined in a series of mesoporous materials displaying different texture and pore morphology. In all cases, hydrogen solubility increases dramatically over bulk values when the liquid size is reduced down to 5-15 nm. In the case of coarse-grained and mesostructured materials, this 'oversolubility' effect is apparently ascribed to a role of surface excess concentrations at mesoconfined gas/liquid interfaces. However, in the case of n-hexane confined in silica aerogel, much higher values are observed. We argue about a possible role of liquid reconstruction, providing higher molecular order in the liquid, to explain this result. (C) 2009 Elsevier B.V. All rights reserved.