Self-assembled monolayers of hemispherical poly(amidoamine) dendrimer were prepared on a gold substrate via Au-S bond. The dendrimer layer with succinic acid showed strong wettability resulting from the densely packed hydrophilic group and 3-D structure. In this report, we suggest that dendrimer is an attractive tool for the design of surface properties and has the possibility to control the surface not only chemically but also physicochemically.