화학공학소재연구정보센터
Korean Journal of Chemical Engineering, Vol.11, No.2, 119-126, April, 1994
APPLICATION OF ADAPTIVE CONTROL WITH RULE-BASES TO CELL RECYCLED CONTINUOUS BIOREACTOR FOR ETHANOL PRODUCTION
An adaptive control algorithm with rule-bases was developed for cell recycled continuous bioreactor. Ethanol fermentation by Saccharomyces cerevisiae was used as a model system. Since the developed algorithm employed the fermentation model, it was possible to estimate the physical state of the system. Five rule-bases were obtained from the experiments and used to adjust the control input. Good control performance was observed using a rule-based STR(self-tuning regulator)compared to the result using conventional STR. When disturbances were given, rule-based adaptive control scheme showed faster recovery of setpoint. The rule-based STR developed in this study was stable, robust and showed good tracking performance.
  1. Bauer S, Ziv E, Biotechnol. Bioeng., 18, 81 (1976) 
  2. Yano T, Kobayashi T, Shimizu S, J. Ferment. Technol., 56, 416 (1978)
  3. Cysewski GR, Wilke CR, Biotechnol. Bioeng., 18, 1297 (1976) 
  4. Cysewski GR, Wilke CR, Biotechnol. Bioeng., 18, 1315 (1976) 
  5. Ghose TK, Tyagi RD, Biotechnol. Bioeng., 21, 1387 (1979) 
  6. Ghose TK, Tyagi RD, Biotechnol. Bioeng., 21, 1401 (1979) 
  7. Cysewski GR, Wilke CR, Biotechnol. Bioeng., 19, 1125 (1977) 
  8. Margaritis A, Wilke CR, Biotechnol. Bioeng., 20, 709 (1978) 
  9. Margaritis A, Wilke CR, Biotechnol. Bioeng., 20, 727 (1978) 
  10. Cysewski GR, Wilke CR, Biotechnol. Bioeng., 20, 1421 (1978) 
  11. Lonsdale HK, J. Membr. Sci., 10, 81 (1982) 
  12. Rogers PL, Lee KJ, Tribe DE, Proc. Biochem., 15, 7 (1980)
  13. Hoffmann H, Kuhlmann W, Meyer HD, Schugerl K, J. Membr. Sci., 22, 235 (1985) 
  14. Nishizawa Y, Mitani Y, Tamai M, Nagai S, J. Ferment. Technol., 61, 599 (1983)
  15. Cheryan M, Mehaia MA, Proc. Biochem., 204 (1984)
  16. Lee CW, Chang HN, Biotechnol. Bioeng., 29, 1105 (1987) 
  17. Lafforgue C, Malinowski J, Goma G, Biotechnol. Lett., 9, 347 (1987) 
  18. Jarzebski AB, Malinowski JJ, Goma G, Biotechnol. Bioeng., 34, 1225 (1989) 
  19. Kim TS, Lee SH, Son SM, Kwon YJ, Pyun YR, Korean J. Appl. Microbiol. Biotechnol., 19, 419 (1991)
  20. Taniguchi M, Kotani N, Kobayashi T, J. Ferment. Technol., 65, 179 (1987) 
  21. Hayakawa K, Sansawa H, Nagamune T, Endo I, J. Ferment. Technol., 70, 404 (1990)
  22. Lee YL, Chang HN, Biotechnol. Bioeng., 36, 330 (1990) 
  23. Malinowski JJ, Lafforgue C, Goma G, J. Ferment. Technol., 65, 319 (1987) 
  24. Shi Z, Shimizu K, Watanabe N, Kobayashi T, Biotechnol. Bioeng., 33, 999 (1989) 
  25. Astrom KJ, Wittenmark B, Adaptive Control, Addison-Wesley, New York (1989)
  26. Takamatsu T, Shioya S, Okada Y, Kanda M, Biotechnol. Bioeng., 27, 1675 (1985) 
  27. Dochain D, Bastin G, Automatica, 20, 621 (1984) 
  28. Williams D, Yousefpour P, Wellington EMH, Biotechnol. Bioeng., 28, 631 (1986) 
  29. Ko KYJ, Mcinnis BC, Goodwin GC, Automatica, 18, 727 (1982) 
  30. Shi Z, Shimizu K, Watanabe N, Kobayashi T, J. Ferment. Bioeng., 70, 415 (1990) 
  31. Lee JW, Yoo YJ, Korean J. Biotechnol. Bioeng., 6, 263 (1991)
  32. Lee JW, Yoo YJ, Korean J. Appl. Microbiol. Bioeng., 20, 597 (1992)