In this work. Ni(OH)(2) nanoplates grown on the Cu substrate were synthesized and characterized by scanning electron microscopy (SEM). X-ray powder diffraction (XRD). and X-ray photoelectron spectroscopy (XPS). Then a novel Cu-Ni(OH)(2) modified glass carbon electrode (Cu-Ni(OH)(2)/GCE) was fabricated and evaluated by electrochemical impedance spectroscopy (EIS). cyclic voltammetry (CV). and typical amperometric response (i-t) method Exhilaratingly, the Cu-Ni(OH)(2)/GCE shows significant electrocatalytic activity toward the reduction of H2O2 At an applied potential of-0 1 V, the sensor produces an ultrahigh sensitivity of 408 1 mu A mM(-1) with a low detection limit of 1.5 mu M (S/N = 3) The response time of the proposed electrode was less than 5s What's more, the proposed sensor displays excellent selectivity, good stability, and satisfying repeatability. (C) 2010 Elsevier Ltd All rights reserved