A new type of solid base catalyst has been prepared by loading of CaO on thermally activated fly ash, with the aim of being used as heterogeneous catalyst for fine chemical production. The prepared fly ash supported calcium oxide catalyst (FAC) was characterized by FT-IR spectroscopy, X-ray diffraction analysis, Scanning Electron Microscopy and atomic absorption spectroscopy. The catalytic activity of FAC was evaluated by Knoevenagel condensation of benzaldehyde and ethyl cyanoacetate as model test reaction under optimized conditions. The catalyst gave very high conversion (87%) of benzaldehyde to desired product ethyl (E)-alpha-cyanocinnamate with high purity. The catalyst was completely recyclable without significant loss in activity up to three reaction cycles, which confers its stability during reaction unlike commercial catalysts. Moreover this catalyst shows a promising future in providing environmentally clean process for the industrial sector. (C) 2010 Elsevier B.V. All rights reserved.