In this work, experiments to examine the liquid-phase adsorption features of sepiolite and pansil have been conducted with synthetic dye wastewaters prepared from commercial grade dye, methylene blue (MB). The adsorption experimental results were analyzed in terms of the equilibrium adsorption capacity and equilibrium time. The Langmuir, Freundlich, and Sips adsorption models are applied to describe the isotherm equilibrium and to determine some parameters. The Sips model agrees well with the experimental data, and the pseudo-second-order kinetic model reproduces properly the kinetic experimental data of the system MB sepiolite. The highest MB adsorption was obtained at acid pH for sepiolite and at basic pH for pansil. Besides, several kinetics models were employed to study the adsorption mechanism of MB on sepiolite.