In this communication, we have developed a feed forward artificial neural network algorithm for estimating dissociation pressures of binary hydrates of tert-butylamine + methane and tert-butylamine + hydrogen, as a function of temperature and concentration Of tert-butylamine in aqueous solution. To develop this algorithm, experimental data reported in the literature on the dissociation pressures of the aforementioned binary hydrates have been used. It is shown that this ANN algorithm can be regarded as a useful tool to model these hydrate systems.