Journal of Applied Polymer Science, Vol.118, No.6, 3269-3273, 2010
Terminal-Specific PEGylation of Polypeptides in a Dilute Solution
PEGylations of polypeptides with a four-arm PEG (polyethylene glycol) in a dilute DMSO solution resulted in a successful conjugation with terminal specificity, which supports an intriguing PEGylation mechanism via conformational and kinetic control. (C) Crown in the Right of Canada. J Appl Polym Sci 118: 3269-3273, 2010