The simultaneous reduction of NO and N2O has been investigated on Pt-based catalysts supported on gamma-Al2O3 and perovskite materials (LaFeO3). Particular attention has been paid to the catalyst resistance to thermal sintering processes occurring under reaction conditions at elevated temperature in the presence of oxygen and water. Bulk and surface modifications have been examined using appropriate physicochemical techniques (H-2-TPR, XPS, and HRTEM) and have been tentatively correlated to the catalytic performances in terms of activity and selectivity. It has been found that a significant particle growth occurs on 4 wt.% Pt/gamma-Al2O3 having a strong detrimental effect on the conversion of N2O at high temperature. On the other hand, 4 wt.% Pt/LaFeO3 exhibits a higher resistance to thermal sintering. Such a behaviour has been explained by the occurrence of strong metal/support interactions highlighted by high resolution TEM observations. The formation of epitaxially oriented Pt particles on the LaFeO3 crystal lattice during thermal activation, still observable after thermal ageing would partly explain the best resistance of 4 wt.% Pt/LaFeO3 to deactivation towards the conversion of N2O at high temperature. Hence, supported catalysts on LaFeO3 with lower Pt loading were prepared. It has been finally found a striking enhancement of the catalytic performances, opening a new practical interest for minimising the noble metal loading. (C) 2010 Elsevier Inc. All rights reserved.