화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Applied Chemistry for Engineering, Vol.22, No.2, 119-124, April, 2011
Export Citation
항생펩타이드의 기능과 적용분야
The Function and Application of Antibiotic Peptides
이종국, , 박윤경1, †
  • 조선대학교 단백질소재연구센터
  • 1조선대학교 자연과학대학 생명공학과
Jong-Kook Lee, Ramamourthy Gopal, and Yoonkyung Park1, †
  • Research Center for Proteinaceous Materials (RCPM), Chosun University, Gwangju 501-759, Korea
  • 1Department of Biotechnology, Chosun University, Gwangju 501-759, Korea
E-mail:
초록
현재, 사람들은 많은 병에 노출되어 있다. 산업화의 빠른 변화는 생산시설의 자동화, 정보.통신 산업기술의 발달로 삶의 질이 향상되었으나, 신체활동의 감소와 환경오염으로 인해 환경적 스트레스와 병원균 감염 반응에 대한 인간의 면역체계가 악화되었다. 아울러 현재 약물의 오.남용으로 다재약물내성을 갖는 미생물들(multidrug-resistant microbes)과 암세포(tumor)의 출현으로 인해 새로운 항생제 개발이 시급하다. 그들 중 하나가 항생 펩타이드(antibiotic peptide)로 기존 약물과 비교하면 약물저항성이 거의 일어나지 않는다. 여러 가지 항생활성을 가지는 펩타이드들은 다양한 생명체로부터 동정되고 있다. 이 논문은 항생 펩타이드들의 활성과 적용분야에 대해 논하려 한다.
Currently, people are exposed to many harmful diseases. Therefore, there are many schemes, such as automation of productive facilities, development of information and communication technology, enhanced the quality of human life and wealth. However, these processes lead to weakened immune system. Thus, people are more vulnerable to infections from pathogens and environmental stress. Misuse and abuse of drugs resulted in the rapid emergence of multidrug-resistant microbes and tumors, therefore, to find new antibiotics are urgently needed. One of them is a peptide-antibiotic, that is not or less occurred a drug-resistance, comparing to conventional drugs. Peptides with various antibiotic activities have been identified from life organisms. The present review provides an overview of activities and application of peptide antibiotics.
Keywords:disease;immune system;multidrug-resistant microbes;conventional drugs;peptides
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