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Journal of Molecular Catalysis A-Chemical, Vol.319, No.1-2, 1-29, 2010
Pd-0- and Pd-II-catalyzed oxaheterocyclization of substrates having both an allylic leaving group and a hydroxylated tether
This review surveys the different asymmetric and non-asymmetric Pd-catalyzed heterocyclizations of allylic alcohols, esters, ethers, carbonates, amines or silanes and vinyl epoxides, which bear a hydroxylated tether. Lactones or carbonates have been obtained from reactions carried out under carbon oxide or carbon dioxide atmosphere, respectively. The dichotomy between the mechanisms of the Pd-0 and Pd-II processes is emphasized. (C) 2009 Elsevier BY. All rights reserved.
Keywords:Palladium;Catalysis;Heterocyclization;Alcohol;Carbonylation;Lactonisation;Carbonatation;Mechanism