MATHEMATICAL MODELING OF FED-BATCH BUTA- NOL FERMENTATION WITH SIMULTANEOUS PERVAPORATION

Park CH; Geng CQ

Korean Journal of Chemical Engineering, Vol.13, No.6, 612-619, November, 1996

A mathematical model was developed to describe a fed-batch acetone-butanol-ethanol (ABE) fermentation with simultaneous pervaporation. The model predicted satisfactorily batch or fed- batch fermentation with or without pervaporation by introducing a parameter reflecting cell activity loss during fed-batch fermentation with pervaporation. The model also predicted the effect of membrane area, membrane thickness, and sweep air flow rate on glucose consumption rate and residual butanol concentration in the fermentation broth. Glucose con- sumption rate increased by 30% by either doubling the membrane area or decreasing mem- brane thickness by half.

Keywords:Mathematical Model;Butanol Fermentation;Prevaporation;Membrane Area and Thickness;Sweep Air Flow Rate

[References]

Bailey H, Ollis DF, "Biochemical Engineering Fundamentals," McGraw-Hill, New York (1986)
Charpra SC, Canale RP, "Numerical Methods for Engineers," McGraw-Hill, New York (1988)
Contois DE, J. Gen. Microbiol., 21, 40 (1959)
Costa JM, Moreira AR, Am. Chem. Soc. Symp. Ser., 207, 501 (1983)
Fond O, Matta-El-Amouri G, Petitdemange H, Engasser JM, Appl. Microbiol. Biotechnol., 22, 195 (1985)
Geng C, Ph.D. Dissertation, "Acetone-Butanol-Ethanol Fermentation and Pervaporation by Clostridium Acetobutylicum B18," University of Minnesota, St. Paul, U.S.A. (1995)
Geng QH, Park CH, Biotechnol. Bioeng., 43(10), 978 (1994)
Geng Q, Park CH, Biotechnol. Lett., 15, 421 (1993)
Geng Q, Park CH, Janni K, Korean J. Chem. Eng., 12(3), 378 (1995)
Gottschalk G, "Bacterial Metabolism," Springer-Verlag, NY (1986)
Groot WJ, Den Reyer MCH, vander Lans RGJM, Luyben KAM, Chem. Eng. J., 46, B11 (1991)
Jarzebski AB, Goma G, Soucaille P, Bioprocess Eng., 7, 357 (1992)
Park CH, Geng Q, Rogers P, Appl. Microbiol. Biotechnol., 39, 148 (1993)
Park CH, Okos MR, Wankat PC, Biotechnol. Prog., 7, 185 (1991)
Roels JA, "Energetics and Kinetics in Biotechnology," Elsevier Biomedical Press, New York (1983)
Shukla R, Kang W, Sirkar KK, Biotechnol. Bioeng., 34, 1158 (1989)
Srivastava AK, Volesky B, Biotechnol. Bioeng., 12, 693 (1990)
Volesky B, Votruba J, "Modeling and Optimization of Fermentation Processes," Elsevier, New York (1992)
Votruba J, Volesky B, Yerushalmi L, Biotechnol. Bioeng., 28, 247 (1986)

[Referenced By]

[1] Bailey H, Ollis DF, "Biochemical Engineering Fundamentals," McGraw-Hill, New York (1986)

[2] Charpra SC, Canale RP, "Numerical Methods for Engineers," McGraw-Hill, New York (1988)

[3] Contois DE, J. Gen. Microbiol., 21, 40 (1959)

[4] Costa JM, Moreira AR, Am. Chem. Soc. Symp. Ser., 207, 501 (1983)

[5] Fond O, Matta-El-Amouri G, Petitdemange H, Engasser JM, Appl. Microbiol. Biotechnol., 22, 195 (1985)

[6] Geng C, Ph.D. Dissertation, "Acetone-Butanol-Ethanol Fermentation and Pervaporation by Clostridium Acetobutylicum B18," University of Minnesota, St. Paul, U.S.A. (1995)

[7] Geng QH, Park CH, Biotechnol. Bioeng., 43(10), 978 (1994)

[8] Geng Q, Park CH, Biotechnol. Lett., 15, 421 (1993)

[9] Geng Q, Park CH, Janni K, Korean J. Chem. Eng., 12(3), 378 (1995)

[10] Gottschalk G, "Bacterial Metabolism," Springer-Verlag, NY (1986)

[11] Groot WJ, Den Reyer MCH, vander Lans RGJM, Luyben KAM, Chem. Eng. J., 46, B11 (1991)

[12] Jarzebski AB, Goma G, Soucaille P, Bioprocess Eng., 7, 357 (1992)

[13] Park CH, Geng Q, Rogers P, Appl. Microbiol. Biotechnol., 39, 148 (1993)

[14] Park CH, Okos MR, Wankat PC, Biotechnol. Prog., 7, 185 (1991)

[15] Roels JA, "Energetics and Kinetics in Biotechnology," Elsevier Biomedical Press, New York (1983)

[16] Shukla R, Kang W, Sirkar KK, Biotechnol. Bioeng., 34, 1158 (1989)

[17] Srivastava AK, Volesky B, Biotechnol. Bioeng., 12, 693 (1990)

[18] Volesky B, Votruba J, "Modeling and Optimization of Fermentation Processes," Elsevier, New York (1992)

[19] Votruba J, Volesky B, Yerushalmi L, Biotechnol. Bioeng., 28, 247 (1986)