Journal of the American Chemical Society, Vol.132, No.8, 2522-2522, 2010
Copper-Catalyzed Direct Alkynylation of Electron-Deficient Polyfluoroarenes with Terminal Alkynes Using O-2 as an Oxidant
A copper-catalyzed direct alkynylation of electron-deficient polyfluoroarenes with a wide range of terminal alkynes is realized for the first time. The reaction proceeds under mild conditions with O-2 as an oxidant.