Journal of the American Chemical Society, Vol.132, No.10, 3262-3262, 2010
Chiral Silver Amide-Catalyzed Enantioselective [3+2] Cycloaddition of alpha-Aminophosphonates with Olefins
The first catalytic asymmetric [3 + 2] cycloadditions of Schiff bases of alpha-aminophosphonates with olefins have been developed. Chiral silver amide complexes bearing (R)-DTBM-SEGPHOS worked well as catalysts for the first time, and proline phosphonic analogues were obtained in high yields with excellent exo- and enantioselectivities.