Journal of the American Chemical Society, Vol.132, No.43, 15179-15181, 2010
Efficient Ring-Closing Metathesis of Alkenyl Bromides: The Importance of Protecting the Catalyst during the Olefin Approach
We present the first productive ring-closing metathesis reaction that leads to the construction of cyclic alkenyl bromides. Efficient catalysis employing commercially available Grubbs II catalyst is possible through appropriate modification of the starting bromoalkene moiety.