A new specific method to measure adsorption enthalpy on supported metallic nanoparticles has been developed. This method is based on gas chromatography measurements, and it allows the calculation of adsorption enthalpies on metallic nanoparticles while neglecting the effect of the supporting particle. In this paper, we discuss the specific case of the adsorption of benzene on the surface of silica-supported gold nanoparticles. The results show a good correlation with similar values found in the literature.